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Listar por autor "Calderón Montaño, José Manuel"
Mostrando ítems 1-20 de 46
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Artículo
5-Aza-2'-deoxycytidine causes replication lesions that require Fanconi anemia-dependent homologous recombination for repair
Orta Vázquez, Manuel Luis; Calderón Montaño, José Manuel; Domínguez García, Inmaculada; Pastor Carrillo, Nuria María; Burgos Morón, Estefanía; López Lázaro, Miguel; Cortés, Felipe; Mateos Cordero, Santiago; Helleday, Thomas (Oxford University Press, 2013)5-Aza-2'-deoxycytidine (5-azadC) is a DNA methyltransferase (DNMT) inhibitor increasingly used in treatments of hematological ...
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Artículo
A hydroalcoholic extract from the leaves of Nerium oleander inhibits glycolysis and induces selective killing of lung cancer cells
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; Orta Vázquez, Manuel Luis; Mateos Cordero, Santiago; López Lázaro, Miguel (Georg Thieme Verlag, 2013)Recent evidence suggests that cardiac glycosides might be used for the treatment of cancer. The ornamental shrub Nerium ...
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Artículo
Anticancer Activities of Meroterpenoids Isolated from the Brown Alga Cystoseira usneoides against the Human Colon Cancer Cells HT-29
Zbakh, Hanaa; Zubía, Eva; Reyes, Carolina de los; Calderón Montaño, José Manuel; Motilva Sánchez, Virginia (MDPI, 2020)Colorectal cancer (CRC) is one of the most common types of cancers and a leading cause of cancer death worldwide. The ...
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Artículo
Artificial Diets Based on Selective Amino Acid Restriction versus Capecitabine in Mice with Metastatic Colon Cancer
Jiménez Alonso, Julio José; Guillén Mancina, Emilio; Calderón Montaño, José Manuel; Jiménez González, Víctor; Díaz Ortega, Patricia; Burgos Morón, Estefanía; López Lázaro, Miguel (MDPI, 2022)New therapies are needed to improve the low survival rates of patients with metastatic colon cancer. Evidence suggests ...
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Artículo
Artificial Diets with Altered Levels of Sulfur Amino Acids Induce Anticancer Activity in Mice with Metastatic Colon Cancer, Ovarian Cancer and Renal Cell Carcinoma
Jiménez Alonso, Julio José; Guillén Mancina, Emilio; Calderón Montaño, José Manuel; Jiménez González, Víctor; Díaz Ortega, Patricia; Burgos Morón, Estefanía; López Lázaro, Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Sulfur-containing amino acids methionine (Met), cysteine (Cys) and taurine (Tau) are common dietary constituents with ...
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Artículo
Artificial Diets with Selective Restriction of Amino Acids and Very Low Levels of Lipids Induce Anticancer Activity in Mice with Metastatic Triple-Negative Breast Cancer
Guillén Mancina, Emilio; Jiménez Alonso, Julio José; Calderón Montaño, José Manuel; Jiménez González, Víctor; Díaz Ortega, Patricia; Burgos Morón, Estefanía; López Lázaro, Miguel (Multidisciplinary Digital Publishing Institute (MDPI), 2023)Current treatments for patients with metastatic triple negative breast cancer (TNBC) are generally ineffective. This ...
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Trabajo Fin de Grado
Avances en el tratamiento de la fibromialgia
Ramírez Díaz, María Victoria (2022)La fibromialgia es considerada como un síndrome que produce un marcado dolor crónico en el aparato locomotor, y se encuentra ...
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Artículo
Carbohydrate-Based NK1R Antagonists with Broad-Spectrum Anticancer Activity
Recio Jiménez, Rocío; Lerena Pérez, Patricia; Pozo Torres, Esther; Calderón Montaño, José Manuel; Burgos Morón, Estefanía; López Lázaro, Miguel; Valdivia Giménez, Victoria Esther; Pernia Leal, Manuel; Mouillac, Bernard; Organero, Juan Ángel; Khiar, Noureddine; Fernández Fernández, Inmaculada (American Chemical Society, 2021)NK1R antagonists, investigated for the treatment of several pathologies, have shown encouraging results in the treatment ...
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Artículo
Cells Deficient in the Fanconi Anemia Protein FANCD2 are Hypersensitive to the Cytotoxicity and DNA Damage Induced by Coffee and Caffeic Acid
Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Orta Vázquez, Manuel Luis; Guillén Mancina, Emilio; Mateos Cordero, Santiago; López Lázaro, Miguel (MDPI AG, 2016)Epidemiological studies have found a positive association between coffee consumption and a lower risk of cardiovascular ...
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Artículo
Chirality influence on the cytotoxic properties of anionic chiral bis(N-heterocyclic carbene)silver complexes
Carrasco Carrasco, Carlos Jesús; Montilla Ramos, Francisco Javier; Álvarez González, Eleuterio; Calderón Montaño, José Manuel; López Lázaro, Miguel; Galindo del Pozo, Agustín (Elsevier, 2022)Complexes Na3[Ag(NHCR)2], 2a-e and 2b’-c’, where NHCR is a N-heterocyclic carbene of the 2,2′-(1H-2λ3,3λ4-imidazole-1,3-diyl)dicarboxylate ...
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Artículo
Cholesterol levels affect the performance of aunps-decorated thermo-sensitive liposomes as nanocarriers for controlled doxorubicin delivery
García, Mónica C.; Naitlho, Nabila; Calderón Montaño, José Manuel; Drago, Estrella; Rueda Rueda, Manuela; Longhi, Marcela; Rabasco Álvarez, Antonio María; López Lázaro, Miguel; Prieto Dapena, Francisco; González Rodríguez, María Luisa (Multidisciplinary Digital Publishing Institute (MDPI), 2021)Stimulus-responsive liposomes (L) for triggering drug release to the target site are particularly useful in cancer therapy. ...
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Artículo
Comment on ‘Quiescence and γH2AX in neuroblastoma are regulated by Ouabain/Na,K-ATPase': ouabain and cáncer
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; López Lázaro, Miguel (Nature Publishing Group, 2013) -
Artículo
Consumption of the Dietary Flavonoids Quercetin, Luteolin and Kaempferol and Overall Risk of Cancer - A Review and Meta-Analysis of the Epidemiological Data
López Lázaro, Miguel; Burgos Morón, Estefanía; Tena, J.D.; Sanz, I.; Sainz, J; Calderón Montaño, José Manuel (Biomedical Publisher, 2013)Numerous epidemiological and preclinical studies suggest that flavonoids may play an important role in the decreased risk ...
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Artículo
DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
Marchena Cruz, Esther; Camino, Lola P.; Bhandari, Jay; Pinela Da Silva, Sonia Cristina; Marqueta Gracia, José Javier; Amdeen, Shahad A.; Guillén Mendoza, Cristina; García Rubio, María Luisa; Calderón Montaño, José Manuel; Xue, Xiaoyu; Luna Varo, Rosa María; Aguilera López, Andrés (Elsevier, 2023)Unscheduled R loops can be a source of genome instability, a hallmark of cancer cells. Although targeted proteomic ...
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Artículo
Design, synthesis and biological studies of a library of NK1-Receptor Ligands Based on a 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyran core: Switch from antagonist to agonist effect by chemical modification
Recio Jiménez, Rocío; Vengut-Climent, Empar; Mouillac, Bernard; Orcel, Hélène; López Lázaro, Miguel; Calderón Montaño, José Manuel; Álvarez González, Eleuterio; Khiar, Noureddine; Fernández Fernández, Inmaculada (Elsevier, 2017)A library of 5-arylthiosubstituted 2-amino-4,6-diaryl-3-cyano-4H-pyrans has been synthesized as a new family of non-peptide ...
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Artículo
Dichloroacetate, 2-Deoxyglucose and a Hydroalcoholic Extract from the Skin of the Fruit of Solanum melongena (Aubergine) Induce Selective Anticancer Activity against Melanoma Cells
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; Martínez Sánchez, Sara María; López Lázaro, Miguel (Biomedical Publisher, 2013)Prognosis of melanoma patients with metastatic disease is very poor. For example, over 95% of melanoma patients with three ...
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Artículo
Effect of DNA repair deficiencies on the cytotoxicity of resveratrol
López Lázaro, Miguel; Burgos Morón, Estefanía; Calderón Montaño, José Manuel; Orta Vázquez, Manuel Luis; Mateos Cordero, Santiago (2015)Numerous preclinical studies have shown that the naturally-occurring polyphenol resveratrol may produce health-beneficial ...
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Tesis Doctoral
Evaluación de nuevas estrategias para el desarrollo de terapias anticancerosas selectivas
Calderón Montaño, José Manuel (2013-07-01)Evaluación de nuevas estrategias para el desarrollo de terapias anticancerosas selectivas El cáncer es una enfermedad ...
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Artículo
Evaluating the cancer therapeutic potential of cardiac glycosides
Calderón Montaño, José Manuel; Burgos Morón, Estefanía; Orta Vázquez, Manuel Luis; Maldonado Navas, Dolores; García Domínguez, Irene; López Lázaro, Miguel (Hindawi Publishing Corporation, 2014)Cardiac glycosides, also known as cardiotonic steroids, are a group of natural products that share a steroid-like structure ...
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Trabajo Fin de Grado
Farmacoterapia de la leucemia linfoblástica aguda
Martín Martín, María (2021)A pesar de que la leucemia linfoblástica aguda (LLA) es una enfermedad con una baja incidencia en la población adulta, ...